Glutamic acid
Glutamic acid (àgékúrú sí Glu tàbí E; tí ó ń kóòdù fún GAA or GAG) jẹ́ α-amino tí wọ́n ń lò lati ṣèdá àwọn protein nínú ara. Ó ní α-amino lẹ́gbẹ́ kan (èyí tí ó ní agbára −NH3+ lábẹ́ ààyé), àti α-carboxylic acid lẹ́gbẹ́ kan (èyí tí kò ní agbára −COO− lábẹ́ ààyé), àti carboxylic acid tí ó somọ́ lẹ̀gbẹ́, tí a sì kó wọn pọ́ sí àwọn tí kò lágbára lati túká sómi (ní pH ara), aliphatic amino acid. Kò ṣe pàtàkì lára ènìyàn nítorí ara lè ṣẹ̀dá rẹ̀. Ní ìmọ̀ àrùn ọpọlọ, carboxylate anion ti glutamate jẹ́ ohun tí ó máa ń fún neurotransmitter lágbára lati ṣisẹ́ ìtají àwọn ètò ọpọlọ.[4] Base tó ní hydrogen ion jẹ́ glutamate; tí radical rẹ̀ jẹ́ sì glutamyl.
| Glutamic acid | |
|---|---|
| |
| |
| |
2-Aminopentanedioic acid | |
| Àwọn orúkọ mìíràn | 2-Aminoglutaric acid |
| Identifiers | |
| CAS number | 56-86-0 (L isomer) |
| ChEBI | CHEBI:18237 |
| SMILES | C(CC(=O)O)C(C(=O)O)N
|
| InChI | 1/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)
|
| InChI key | WHUUTDBJXJRKMK-UHFFFAOYAD |
| ChemSpider ID | 591 |
| Properties | |
| Fọ́múlà mólékùlù | C5H9NO4 |
| Ìkójọ mọ́lù | 147.13 g mol−1 |
| Appearance | white crystalline powder |
| Density | 1.4601 (20 °C) |
| Ojúàmì ìyọ́ |
199 °C, 472 K, 390 °F |
| Solubility in water | 7.5 g/L (20 °C)[1] |
| Solubility | 0.00035g/100g ethanol (25 °C)[2] |
| Acidity (pKa) | 2.10, 4.07, 9.47 [3] |
| Hazards | |
| NFPA 704 |
 1
2
0
|
| Àdàkọ:Cross(what is this?) (verify) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Ẹ̀kọ́ ẹ̀lá
àtúnṣeìsomọ́ ẹlẹ́gbẹ́ fún iṣẹ́ ṣiṣe carboxylic acid ní pKa tí ó jẹ́ 4.1.
Ìṣẹ̀dá
àtúnṣe| Reactants | Products | Enzymes |
|---|---|---|
| Glutamine + H2O | → Glu + NH3 | GLS, GLS2 |
| NAcGlu + H2O | → Glu + Acetate | N-acetyl-glutamate synthase |
| α-ketoglutarate + NADPH + NH4+ | → Glu + NADP+ + H2O | GLUD1, GLUD2[5] |
| α-ketoglutarate + α-amino acid | → Glu + α-keto acid | transaminase |
| 1-Pyrroline-5-carboxylate + NAD+ + H2O | → Glu + NADH | ALDH4A1 |
| N-formimino-L-glutamate + FH4 | → Glu + 5-formimino-FH4 | FTCD |
| NAAG | → Glu + NAA | GCPII |
Àwọn ìtọ́kasí
àtúnṣe- ↑ "Ẹda pamosi". Archived from the original on 2016-09-11. Retrieved 2016-07-02.
- ↑ Belitz, H.-D; Grosch, Werner; Schieberle, Peter (2009-02-27). Food Chemistry. ISBN 9783540699330. https://books.google.com/?id=xteiARU46SQC&pg=PA15.
- ↑ http://www.cem.msu.edu/~cem252/sp97/ch24/ch24aa.html
- ↑ Robert Sapolsky (2005). "Biology and Human Behavior: The Neurological Origins of Individuality, 2nd edition". The Teaching Company. "see pages 19 and 20 of Guide Book"
- ↑ Grabowska, A.; Nowicki, M.; Kwinta, J. (2011). "Glutamate dehydrogenase of the germinating triticale seeds: Gene expression, activity distribution and kinetic characteristics". Acta Physiologiae Plantarum 33 (5): 1981–1990. doi:10.1007/s11738-011-0801-1.